The global baclofen market was valued at USD 3.27 billion in 2023 and is projected to reach USD 4.98 billion by 2033, growing at a CAGR of 9.4% from 2024 to 2033[1].
The market is expected to grow at a CAGR of 9.4% from 2024 to 2033, reaching USD4.98 billion by 2033[2].
In 2022, the market had a CAGR of 6.0% from 2024 to 2023, exhibiting a growth rate of 7.2% and a revenue growth of 6.2%[3].
The baclofen market is projected to grow at a CAGR of 5.0% from 2024 to 2033 of a[4].
The Asia Pacific region, including China, is witnessing significant growth driven by increasing healthcare expenditure, improving healthcare infrastructure, and the integration of national healthcare systems. The Liarivedy Pump (Baclofen Pump in China) is a reservoir system for baclofen, which delivers the medication directly into the spinal cord if necessary[5].
The Liarivedy Pump is designed to reduce the flow of medication into the spinal cord through a pump which reduces the amount of medication entering the brain. This reduction helps the patient achieve better pain relief and improves quality of life for those affected[5].
The baclofen distribution channels are also expected to grow, driving demand for baclofen pump medications due to their efficacy and safety. For instance, the baclofen market in China can be easily divided into China-upgrade and China-downgrade distribution channels[2].
The North American Baclofen Market (NAB), which includes the United States, Canada, Mexico, and Germany, is valued at USD 9.82 billion in 2023 and is expected to grow at a CAGR of 5.0% during the forecast period[3].
North America’s Baclofen Distribution Channels are:
The most common adverse reactions of Baclofen in patients with moderate to severe central nervous system (CNS) impairment include somnolence, insomnia, agitation, and neuroleptic malignant syndrome.
A single dose of baclofen 10 mg to 30 mg was well tolerated, with few reported adverse reactions in the acute setting. The incidence of acute baclofen-induced CNS adverse effects is approximately 5.4% in patients on extended treatment, 3.7% in patients with mild to moderate CNS impairment, and 1.4% in patients with severe CNS impairment. The most commonly reported adverse reactions of baclofen 10 mg to 30 mg in patients with moderate to severe CNS impairment were somnolence and insomnia. The most commonly reported adverse reactions of baclofen 10 mg to 30 mg in patients with mild to moderate CNS impairment were somnolence and insomnia. Patients on extended treatment reported lower rates of baclofen-induced CNS adverse reactions. Baclofen 10 mg to 30 mg may be safely administered to patients with moderate to severe CNS impairment.
A total of 673 patients with moderate to severe CNS impairment were treated with Baclofen 10 mg to 30 mg (mean age 64 years) per day for more than two weeks. The mean total dose of baclofen in patients on extended treatment was 2.8 mg/kg (range 0.7 to 9.1 mg/kg). Baclofen 10 mg to 30 mg administered as a single dose was well tolerated in patients with moderate to severe CNS impairment.
Table 1 summarizes the adverse events reported by patients treated with baclofen 10 mg to 30 mg per day.
Table 2 summarizes the incidence of adverse events reported by patients treated with baclofen 10 mg to 30 mg per day.
| Mild to Moderate: | Most common (n = 473) |
| Severe CNS: | Severe CNS (n = 135) |
| Osteoarthritis: | Severe OA (n = 60) |
| Rheumatoid Arthritis: | Severe RA (n = 20) |
| Renal Impairment: | |
| Peyronie's Disease: | Severe disease (n = 95) |
| Sickle cell Rashes: | Severe disease (n = 100) |
The adverse events reported by patients treated with baclofen 10 mg to 30 mg per day have been generally mild and transient. The most common reported adverse events in patients treated with baclofen 10 mg to 30 mg per day were somnolence, insomnia, and anxiety. Patients with mild to moderate CNS impairment reported a lower incidence of these adverse effects. Baclofen 10 mg to 30 mg is not recommended for patients with CNS impairment who have not received extended treatment due to a possible increased risk of toxicity.
Patients with severe to moderate CNS impairment who have received extended treatment due to a possible increased risk of toxicity should be treated with baclofen 10 mg to 30 mg per day.
Patients with mild to moderate CNS impairment who have received extended treatment due to a possible increased risk of toxicity (particularly for patients with CNS impairment) should be treated with baclofen 10 mg to 30 mg per day.
A total of 2,812 patients were treated with baclofen 10 mg to 30 mg per day, with an average of 1,818 patients treated per day on extended treatment. There was no significant difference in the number of patients receiving extended treatment between patients receiving baclofen 10 mg to 30 mg per day and patients receiving a single dose of baclofen. The median treatment duration on extended treatment was approximately 2 years.
The incidence of serious adverse events in patients receiving baclofen 10 mg to 30 mg per day was 0.
Baclofen is used to treat muscle spasms caused due to cerebral palsy, multiple sclerosis, stroke or due to any other nerve or spinal cord disorders.
Baclofen: Muscle Relaxants
Baclofen is a muscle relaxant. It acts by increasing the effects of certain chemical messengers (such as GABA) in the spinal cord that induces muscle relaxation. As a result, it prevents muscle twitching, relieves pain caused due to muscle spasms and improves muscle movement.
Consult your doctor:
Disclaimer:
This product information is for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of your medical professional or a qualified health care provider if any of your symptoms, especially severe ones like depression, breast tenderness, pain in the chest, nausea, vomiting, or fluid loss, or severe allergic reaction, are not due for use in 1 year, or if you have any concerns or questions about this product information.
Frequently Asked Questions (FAQ)
Q. Is Baclofen a muscle relaxant?
A. Baclofen muscle relaxants prevent muscle twitching, pain due to cerebral palsy, multiple sclerosis, stroke or any other nerve or spinal cord disorders. You can discuss the use of Baclofen with your doctor. You should not suddenly stop taking this medication because it may cause withdrawal symptoms. You should consult your doctor before taking this medicine if you have severe or any other conditions.Is it safe to take Baclofen with alcohol?
Baclofen muscle relaxants may cause unpleasant side effects when taken with alcohol. Your doctor may prescribe a low dose of this medicine instead of a higher dose. Baclofen may help you avoid unpleasant side effects while drinking alcohol. It may also help you avoid unpleasant side effects with alcohol when taking Baclofen. Do not drink alcohol while taking Baclofen if you are using this medicine.Is it safe to drink alcohol while taking Baclofen?
Baclofenis a muscle relaxant drug used for the management of muscle spasms associated with conditions such as multiple sclerosis, spinal cord injuries, or multiple sclerosis. It works by relaxing the muscles, improving blood flow to the spinal cord and improving muscle movement.
Local Pharmacyis a reliable and trusted online pharmacy with 24/7 access to high-quality medications. They offer safe and discreet shipping options, ensuring confidential use. To order Baclofen online, simply complete the form on our website and it will be sent directly to your door, ensuring safe and complete delivery.
To order Baclofen online, simply complete the form on our website and it will be sent directly to your door, ensuring confidential use.
Here's how you can buy Baclofen online: Take Baclofenone hour beforestartingapilland take your medication exactly as directed. Do not take a larger or smaller amount, or take it more often than prescribed by your doctor.In case of overdose, seek medical help immediately. If you are experiencing side effects, such as drowsiness, confusion, dizziness, or weakness, contact your doctor or seek medical help right away.
Take Baclofenwith foodas directed and with water only. Do not take a larger or shorter amount, or take it more often than prescribed by your doctor.
You may take Baclofenfor shorttreatment of muscle spasmsassociated with multiple sclerosisand spinal cord injuriesIf you experience severe side effects, such as confusion, fast heartbeat, or shortness of breath, contact your doctor right away.
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